Researcher/PhD (m/f/x) in Molecular Biology / Protein Science

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Faculty of Medicine:

Chair of Biophysics

In order to fill a fixed-term position in part-time (25,89 hours/week = 65 %) at the earliest possible date or by February 15, 2027, we are looking for 1

Researcher/PhD (m/f/x) in Molecular Biology / Protein Science

The Karges Research Group is seeking a highly motivated PhD researcher to join our interdisciplinary program at the interface of molecular biology, medicinal chemistry, biophysics, and translational medicine.

We design and synthesize novel metal complexes, characterize their photophysical properties, and explore their biological activity against target proteins and cancer cells, with a focus on medical applications.

More information: https://www.kargesgroup.ruhr-uni-bochum.de/

The PhD project will investigate the mechanisms of action of novel compounds targeting cancer-relevant proteins.

This includes expressing and characterizing protein targets, studying their interactions with drug-like compounds, analyzing protein modifications and their functional consequences, and developing new biochemical assays.

Promising compounds may then be studied in cancer cell monolayers and 3D tumor organoids, linking molecular mechanisms to biological activity and contributing to new cancer therapies.

The project requires creativity, initiative, and scientific curiosity, and offers room for independent development.

Experience in recombinant protein expression, purification, and handling is advantageous.

We offer a dynamic, collaborative environment combining chemistry, biology, physics, and medicine, with access to cutting-edge methods.

Scope:

part-time

Duration:

fixed-term,

36 Monate

Start:

at the earliest possible date or by February 15, 2027

Apply by:

2026-10-19

We are looking for a motivated and curious researcher who enjoys working at the interface of different scientific disciplines. You have:

We offer:

Further information:

The position is salaried and based on the collective agreement of the Länder (TV-L).

If the personal and collective agreement requirements are met, the employee will receive pay grade E13 TV-L. Further information can be found at https://oeffentlicher-dienst.info/ (in German).

The place of work is Ruhr University Bochum.

The load of teaching will be calculated according to § 3 of Lehrverpflichtungsverordnung (state of North Rhine-Westphalia).

RUB sees itself as a university with an international presence. The campus languages are German and English. Competence in at least one of the two languages and the willingness to learn the other are a prerequisite. RUB provides corresponding free courses for employees.

German language courses are offered by the University Language Center (ZFA) in the field of German as a Foreign Language (DaF).

https://www.daf.ruhr-uni-bochum.de/daf/mitarbeitende/index.html.en

The Staff Council has the right to participate in all selection interviews. At the request of a candidate (m/f/x), it will ensure its participation in the entire procedure. Please contact wpr@rub.de.

The Ruhr-Universität Bochum is one of Germany’s leading research universities, addressing the whole range of academic disciplines. A highly dynamic setting enables researchers and students to work across the traditional boundaries of academic subjects and faculties. To create knowledge networks within and beyond the university is Ruhr-Universität Bochum’s declared aim.

The Ruhr-Universität Bochum stands for diversity and equal opportunities. For this reason, we favour a working environment composed of heterogeneous teams, and seek to promote the careers of individuals who are underrepresented in our respective professional areas. The Ruhr-Universität Bochum expressly requests job applications from women. In areas in which they are underrepresented they will be given preference in the case of equivalent qualifications with male candidates. Applications from individuals with disabilities are most welcome.

persons for further information:

Riccarda Aust

, Tel.: +49 234 32 18035

Travel costs, accommodation costs and loss of earnings or other application costs for job interviews can unfortunately not be reimbursed.

We look forward to receiving your application via our online application portal by 2026-10-19. Please make sure to mention the reference number ANR 6171.

Online application

44801 Bochum

Universitätsstraße 150

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